Urinary neutrophil gelatinase-associated lipocalin: potential biomarker for late-onset sepsis

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Urinary neutrophil-gelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates

Background: Routine diagnostic methods of Vesicoureteral reflux (VUR) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. Therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. The objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...

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Neutrophil gelatinase-associated lipocalin as a biomarker for lupus nephritis.

BACKGROUND One of the challenges of treating patients with lupus nephritis (LN) is to accurately assess disease activity and predict its outcome. Since renal-biopsy cannot be performed routinely, new surrogate biomarkers are needed. METHODS We evaluated neutrophil gelatinase-associated lipocalin (NGAL), to predict renal outcome in LN. Serum and urinary NGAL levels, measured by the enzyme-link...

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urinary neutrophil-gelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates

background: routine diagnostic methods of vesicoureteral reflux (vur) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. the objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...

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Neutrophil gelatinase-associated lipocalin as a potential novel biomarker for ventilator-associated lung injury

Neutrophil gelatinase‑associated lipocalin (NGAL) is a 25‑kDa protein of the lipocalin superfamily and its presence was initially observed in activated neutrophils. It has previously been demonstrated that the expression of NGAL is markedly increased in stimulated epithelia, and is important in the innate immunological response to various pathophysiological conditions, including infection, canc...

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Urinary neutrophil gelatinase-associated lipocalin as a novel biomarker for disease activity in lupus nephritis.

OBJECTIVES Clinical and laboratory markers in current use have limited specificity and sensitivity for predicting the development of renal disease in lupus patients. In this longitudinal study, we investigated whether urinary neutrophil gelatinase-associated lipocalin (uNGAL) predicts active nephritis and renal flares in lupus patients with and without a history of biopsy-proven lupus nephritis...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 2015

ISSN: 0031-3998,1530-0447

DOI: 10.1038/pr.2015.62